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The increases in TGF1 protein expression and SMAD3 phosphorylation induced by high glucose were significantly blocked in PSCs treated with GSH (Figs

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Together, these limitations reveal a fundamental weakness in the translational pipeline: Preclinical models, often biologically reductionist and poorly representative of human pathology, remain inadequate to support the development of interventions with reproducible and clinically relevant neuroprotective effects

Among the sophisticated machines are several large pods that resemble futuristic sarcophagi, one of which spins slowly, dreamily, behind a large glass divider