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Circular RNA HECTD1 mitigates ulcerative colitis by promoting enterocyte autophagy via miR-182-5p/HuR Axis

These medicinesincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)work by mimicking the action of the naturally occurring GLP-1 hormone

Notably, variants of uncertain significance in MC4R did not exert a significant impact on long-term surgical outcomes, indicating that only P/LP variants are associated with compromised long-term efficacy

Kishi T, Hirooka Y, Sunagawa K

349,350 Novel cellular processes and pharmacological targets Although many studies have verified the molecular mechanisms and related drug targets involved in the process of UC occurrence and development, many new insights have been proposed into the pathogenesis of UC in recent years