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Lipopolysaccharide (LPS) on the outer membrane of Gram-negatives are a common PAMP known to induce inflammatory responses (e.g., IL-8) and subsequently inducing mucin secretion (e.g., MUC5AC, MUC5B) (Smirnova et al., 2003

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Furthermore, the type of disease, the duration of the disease, and concurrent treatments (e.g., motor training, see ref [264, 265], or pharmacotherapy, see ref [196]) might interfere with stimulation efficacy [266]

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