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Additionally, studies have shown that Linagliptin significantly improves fasting plasma glucose (FPG) and postprandial glucose (PPG) levels, contributing to overall improved glucose management

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Therefore, our study indicated that GLP-1-derived peptides offer effective pain relief without these significant adverse effects, suggesting their potential as safer alternatives for chronic pain management

Older adults taking GLP-1 receptor agonists may face unique nutritional challenges due to appetite suppression, gastrointestinal side effects, and age-related physiologic changes that increase the risk of undernutrition, dehydration, constipation, and sarcopenia

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