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The results revealed that it significantly increased the levels of Scr and BUN, suppressed the expression of fibronectin and -SMA, increased PTEN, and decreased p-Akt, which correlated with the downregulation of the enhancer of zeste homolog-2 (EZH2) and histone H3 lysine 27 trimethylation (H3K27me3) (Lin et al., 2023)

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DFO could reduce intracellular iron levels and thereby alleviate liver fibrosis induced by CCl4 in rats (Mohammed et al., 2016)

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Reports of incorrect dosing, contamination and unexpected severe reactions have emerged