Lose up to 5% body weight Reduces appetite and cravings Slows digestion to help you feel fuller longer Oral option for those who prefer not to use injections Improves blood sugar control Rybelsus ingredients include: semaglutide (active ingredient), magnesium stearate, microcrystalline cellulose, povidone, and salcaprozate sodium
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist originally developed for type 2 diabetes management and subsequently approved by the FDA for chronic weight management
Pei, Z., Dong, M., Meng, X., Yao, W., Guo, Y., & Wang, F
Insurance coverage improved through 2025 and 2026 but remains patchy for the obesity indication
Participants in the studies were given dosages ranging from 80 milligrams per day (mg/day) to 2,100 mg/day, for 8 36 weeks