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Orlistat has been studied for up to 2 years

Also, while the manufacturers of metformin recommend against breastfeeding while taking the drug, data have shown that metformin is excreted into breast milk in small amounts and adverse effects on infant plasma glucose have not been reported in human studies

Obesity (Silver Spring) 31 , 111122 (2023)

Despite the medical benefits of improved diabetic control and reduced cardiac risk, semaglutide injections can also result in side effects