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Thus, free GSH is the reduced, or antioxidant form, and GSSG is the oxidized form, of GSH

The stress response system also comes under DSIPs influence

While some degree of lean mass decline is physiologically expected during negative energy balance, excessive or disproportionate reductions in skeletal muscle may have important clinical implications in individuals with limited anabolic reserve, defined as a reduced capacity to maintain or restore skeletal muscle mass due to diminished anabolic hormone availability and/or impaired responsiveness of muscle tissue to anabolic stimuli such as testosterone [6,7]

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Provider assessment should document clinical rationale for any GLP-1 use during active breastfeeding