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Similar to the SGLT2 inhibitors [1, 4, 13], GLP-1RAs also mildly reduced systolic and diastolic blood pressure in the trials

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When Cochrane reviewers grade an evidence base as very low quality despite a positive pooled effect, this is usually what they are reacting to: not that the benefit is fake, but that the conditions under which it was measured are the conditions that reliably make benefits look bigger than they are

That delay reduces calorie intake naturally because individuals feel satiated by smaller quantities