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Interactions among various factors, including genetics, the host immune system, microbiome, and environmental factors play an important role in disturbing the intestinal homeostasis, leading to the dysregulated inflammatory response of the GI tract (1, 2, 4-8)

However, keep in mind this study didnt account for other important factors, such as patient compliance with the regimen, other medications perhaps the patient was taking that could affect this

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Ferroptosis inhibition was performed by daily treatment of Fer1 or Lip1 and UAMC-3203, equimolar amounts of the compounds were dissolved in 2% dimethyl sulfoxide (DMSO, Sigma) in 0.9% sterile NaCl