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(Oxf.) 64 , 444449 (2006)

Blocking NNMT is expected to raise SAM availability, but SAM participates in many cellular processes, so research must establish that selectively raising it does not perturb other methylation pathways

The synthesis of nucleotides, the basic building blocks of nucleic acids, is likewise dependent on the raw materials provided by nitrogen metabolism

The regulatory story is not simple, but understanding it is essential for researchers who want to operate within legal frameworks while accessing the compounds they need for their work