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Indeed, NTZ and its active circulating metabolite tizoxanide directly protect from stress-induced apoptosis and necroptosis to alleviate liver damage in acute-on-chronic liver failure rat model (Bobowski-Gerard et al., 2024)
In IRI-induced cardiac injury, arachidonate 15-lipoxygenase (ALOX15) is regarded as the vital enzyme for the mediation of phospholipid peroxidation and ferroptosis in ischemic stage [18] (Fig
Additionally, semaglutide is not recommended for individuals with type 1 diabetes or diabetic ketoacidosis, as it is specifically designed for managing type 2 diabetes
Sci Rep 8 , 5155 (2018)
doi: 10.1177/0394632016651273 [DOI] [PMC free article] [PubMed] [Google Scholar] 166
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