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However, there are a few differences given below

We did not receive public comments on our burden estimates and assumptions, and therefore, we are finalizing our burden estimates as proposed

It pushes usage toward name-brand, FDA-approved possibilities for weight control.

As well, in spirit of your comment re resistance training preeminence versus protein for muscle mass retention, our number one drug of choice for metabolic health has always been lifestyle, particularly Flex5 lifestyle, as medicine (which includes both non-exercise activity time, and Flexio training - Flexio = blending flexibility/balance, resistance exercise and cardio training)

However, their effect on limiting appetite and promoting weight-loss has made them popular with many who struggle to maintain a healthy weight through lifestyle change (creating a modest caloric restriction via diet and exercise)