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The study included a relevant number of participants in the mild, moderate, and severe impairment groups, while comparing to an appropriately baseline matched and sized control reference group

5 Imaging and detection technologies in atherosclerosis 5.1 High-throughput lipidomics and proteomics for atherosclerosis detection Advanced molecular profiling technologies, including lipidomics (comprehensive analysis of lipid species) and proteomics (large-scale characterization of circulating proteins), enable simultaneous quantification of numerous plasma components, allowing early detection of atherosclerotic alterations beyond conventional risk factors

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