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[DOI] [PubMed] [Google Scholar] 49.Mehdi SF et al

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Notably, similar to the native GLP-1, binding of SR18 to GLP-1R also induces structural changes in the conserved motifs (Figure 17) in comparison to the inactive (PDB: 6LN2) GLP-1R (Wu et al., 2020), which is crucial for intracellular signaling of GLP-1R

CONCLUSION This work was supported by the Young Investigator Award 2011 from the Korean Diabetes Association and the Korea Science and Engineering Foundation by the Ministry of Education, Science and Technology (S-2010-1115-000) to Won-Young Lee

The final 20 pounds, however, came with the help of Ozempic