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Other studies have suggested that a member of the MAPKKK family, TAK1 (transforming growth factor -activated kinase) could be an important AMPK upstream kinase in cardiac cells [96], and ATM (ataxia telangiectasia mutated) may also regulate the phosphorylation of Thr172 [97]

Fralick M, Schneeweiss S, Patorno E

This makes it convenient for intranasal administration studies and helps keep lab work efficient

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