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At the time of writing, the FDA has so far noted an absence of safety concerns based on their review to date and is considering exercising enforcement discretion regarding the sale and distribution of (at least some) NAC-containing supplement products

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James SJ, Melnyk S, Fuchs GJ, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW (2008) Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism

10.1038/bjc.2017.96 13 HarrisI

17 In fact, a protective role of GSH against inflammatory pathologies of the lung has been demonstrated by the protective effect of different GSH-precursors in various animal models (Table 2)