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The peptide gained Health Canada and FDA approval for HIV-associated lipodystrophy, establishing a safety and efficacy profile through rigorous clinical evaluation

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Providers should transition to emerging weight loss peptides when a patient experiences intractable side effects (like severe nausea or gastroparesis), when they hit a hard weight loss plateau despite dietary compliance, or when the primary clinical obstacle is documented cellular metabolic resistance rather than hyperphagia (overeating)

Its being researched for its potential to support healing in tendons, ligaments, and the digestive tract