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Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging

A 2012 open-label study on a barley-derived EGF serum reported statistically significant improvements in fine-lines, skin texture, pore size, and uneven skin tone, with changes showing up within the first month of 2x/daily use

Clinica Chimica Acta, 341(1-2), 5563

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Berberine is a bioactive compound extracted from several plants, including barberry, goldenseal, and tree turmeric