While GLP-1s are excellent at stabilizing blood sugar, they can, in rare cases (especially when combined with other diabetes medications), cause hypoglycemia (low blood sugar)
Alternative medication classes should be considered if GLP-1 therapy proves intolerable: SGLT2 inhibitors (such as dapagliflozin, empagliflozin) for type 2 diabetes, which work via a completely different mechanism and rarely cause gastrointestinal side effects DPP-4 inhibitors (such as sitagliptin, linagliptin), which enhance endogenous GLP-1 activity more gently Metformin remains first-line for type 2 diabetes, though it can also cause gastrointestinal side effects Orlistat for weight management, though this also has gastrointestinal side effects of a different nature For weight management specifically, NICE recommends a comprehensive approach including dietary modification, increased physical activity, and behavioural interventions, with or without pharmacotherapy
Joint and Connective Tissue Health Sermorelin promotes collagen production and supports joint integrity, aiding in the repair of cartilage, tendons, and ligaments
GLP-1 Side Effects Litigation The studys findings come as more than 1,300 lawsuits are currently being pursued against the makers of Ozempic, Wegovy, Mounjaro and other similar diabetes and weight loss drugs, each raising similar allegations that a desire for increased profits was placed above consumer safety by failing to research and disclose gastroparesis side effects users may experience
The Bottom Line Vitamin B12 injections can help if your gut doesnt absorb nutrients well or you dont want to take a daily oral supplement