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To this end, cardiovascular diseases, including heart attacks and stroke, are significantly more common among smokers ( The detrimental health effects of smoking can be attributed to a complex interplay of harmful mechanisms that are triggered by more than 7,000 chemicals known to be present in tobacco smoke, of which hundreds are toxic and at least 69 are known carcinogens ( In summary, by examining the intricate ways in which smoking influences the complement system, which, as indicated before, is a fundamental aspect of the immune response, we aim to provide a fresh perspective on the pathophysiological processes underlying smoking-related health conditions

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