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Along those lines, mitochondrial transport reactions that provide substrates for the TCA cycle are enriched among the predicted targets

Xenograft tumor model in nude mice This experiment was approved by the Animal Ethical and Welfare Committee of the Sixth Affiliated Hospital of Sun Yat-sen University (Ethical code: IACUC-2021011501)

Setmelanotide is FDA-approved for rare genetic obesity but expensive and access-restricted

This qualifies the subsequent assessment of variability and the approximately log-normal distribution of bioavailability estimates observed across dose administrations (Fig