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If you are currently taking medications, have existing health conditions, are pregnant or nursing, or are considering any major changes to your health regimen, consult your physician before starting any GLP-1 medication
Regul Toxicol Pharmacol 32(1):5667 Park BK, Boobis A, Clarke S, Goldring CE, Jones D, Kenna JG, Lambert C, Laverty HG, Naisbitt DJ, Nelson S, Nicoll-Griffith DA, Obach RS, Routledge P, Smith DA, Tweedie DJ, Vermeulen N, Williams DP, Wilson ID, Baillie TA (2011) Managing the challenge of chemically reactive metabolites in drug development
Compounded versions of the drugs are easily accessible and affordable for most patients
These molecules are simply too big to penetrate the skin barrier effectively and reach the bloodstream in a way that would produce any meaningful therapeutic effect
only 15% require significant dose modification
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