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Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase

Horses undergoing intense exercise generate more free radicals compared to horses at rest and benefit from additional antioxidant support

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Two commonly used behavioral assays to imply apathy-like deficits are the nest building and sucrose preference test, with nest building reflecting self-care and sucrose preference serving as an indicator of reward perception

So injecting near the injury doesn't give you any extra benefit, and going intramuscular instead of subcutaneous just adds discomfort for no real upside