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When the skin of 8 workers was exposed repeatedly to aqueous solutions of ethylene oxide, all sites of previous contact, with and without a primary reaction, flared up in 3 of them showing pruritus, erythema, and slight oedema, 5 - 9 days after the last exposure (Sexton & Henson, 1950)

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doi:10.1016/j.physio.2009.09.006