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1 The different stages of NAFLD

Macrophage studies demonstrate that GHK-Cu administration shifts these cells from a pro-inflammatory M1 phenotype to a tissue-repairing M2 phenotype, increasing their production of growth factors including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) by 40-60%

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8 In 1939, caloric restriction was subsequently reported to have extended the lifespan of rats and mice, 9 which was the first evidence that the aging process was regulated (Fig