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Second, there was considerable heterogeneity in patient demographics (e.g., age), duration of diabetes, medical history (e.g., baseline HbA1c), treatment history, and concomitant medications for T2DM (e.g., insulin, metformin, or other glucose-lowering agents) among the included studies

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Wu J, Moheimani H, Li S, Kar UK, Bonaroti J, Miller RS, et al

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