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2018;31(3):e12589

10.1016/j.ejphar.2014.01.046 31 DuzelA.VlainicJ.AntunovicM.MalekinusicD.VrdoljakB.SamaraM.et al (2017)

A central player in this process is glutathione peroxidase 4 (GPX4), an enzyme responsible for neutralizing lipid peroxides

Furthermore, the authors indicated that, upon comparison with the literature, the effective concentration was sufficiently low to suggest a signaling role for Epitalon in the cascades of the cellular antioxidant system [57]

iii ) as it has been known for a long time, diet and food intake affect renal gluconeogenesis and water balance ( KO mice likely stems from complex, age-dependent and long-term functional interactions between the brain, pancreatic islets, kidneys and intestines as well as other tissues where NKCC2 may be expressed, even in minimal quantities relative to the kidneys