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The laboratory animals with the Specific Pathogen-Free (SPF) status were procured from the Research Institute of Pharmacology of Living Systems at the Belgorod State University (Belgorod, Russian Federation)

Chronic conditions (tendonitis, joint issues): Typically requires 48 weeks of consistent use to see substantial improvements, with continued benefits over 12+ weeks

The medication carries a risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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The medication has been available since 2012 and is FDA-approved for adults with a body mass index of 30 or higher, or 27 or higher with at least one weight-related health condition