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As this study showed comparable exposures between the 1G and 2G formulations of oral semaglutide that met stringent regulatory bioequivalence criteria, it is considered unlikely that there will be any clinically meaningful differences in efficacy or safety between these formulations

While they offer personalized treatment options, they lack FDA approval, which raises potential safety and efficacy concerns

Insurance coverage for medications like Zepbound can be complex

What are potential side effects

The oral semaglutide 25 mg formulation (the Wegovy pill) is under review by the MHRA, with a decision expected by late 2026