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In a model of septic shock, rats were given a lethal dose of endotoxin (LPS LD50), and T4 was administered via intraperitoneal injection at 100 g/animal immediately following endotoxin and again at 2 and 4 hours after the dose

Data were assessed using the Cochrane Risk of Bias Tool (ROB2), and statistical analyses were conducted with RevMan 5.3

Blood telomere length may also reflect shifts in leukocyte populations rather than a true whole-body anti-aging effect

The peptide does not appear to require cycling for maintained effectiveness, though many users prefer periodic breaks as a precautionary measure

J Lab Clin Med