Robert Kushner: I haven't seen that paper, but what I can say which I thought you were getting to is that when we look at the categorical weight loss in all these trials, so some people lose 5%, 10%, 20%, 25% over the course of the trial, if you then stop the medication, the individuals who lost the greatest amount of body weight actually are the ones that regain it the quickest
The Multi-Dose Hardware Advantage A major bottleneck in the GLP-1 supply chain hasnt just been the active pharmaceutical ingredient (tirzepatide)
reported that quercetin significantly alleviated liver damage in mice by suppressing free radicals and upregulating the levels of antioxidant enzymes including glutathione peroxidase, superoxide dismutase and catalase
If you have diabetes, prediabetes, or take any medications, talk with a licensed clinician before trying weight-loss supplements or metabolic products
A 2024 Swedish study followed 3,249 MS patients for an average of 10.6 years and found that obesity was associated with: 4 43% higher risk of reaching EDSS 3 (moderate disability) 40% higher risk of reaching EDSS 4 (significant walking impairment) More rapid cognitive decline Higher MRI activity showing new brain lesions A German study of 1,066 MS patients found that obese patients reached disability milestones more quickly than those with normal weight
