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But MT-1 has special properties: It selectively activates the MC1R receptor This is the eumelanin switch

Calcium imaging Co-cultures of ND neurons and GLUTag cells were loaded with 5 M Fura-2-acetoxymethyl ester (Molecular Probes) for 30 min in standard saline and Fura-2 calcium imaging was performed with an inverted fluorescence microscope (Olympus IX71, UK) with a 40 oil-immersion objective, coupled to a 75 W xenon arc lamp and a monochromator (Cairn Research, Faversham, UK) controlled by MetaFluor software (Molecular Devices, UK)

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For instance, if youve recently taken a specific medication or undergone a medical procedure, you might be temporarily deferred

BMJ Open 2017;7:e016242.ArticlePubMedPMC 229