Aja, E., Zeng, A., Gray, W., Connelley, K., Chaganti, A., & Jacobs, J
Jump to: Comparison at a glance | Tirzepatide (Mounjaro) | Semaglutide (Wegovy) | Liraglutide (Saxenda) | NHS vs private access | Side effects comparison | Cost analysis | How to choose | Medications in development | Frequently asked questions | Take home message Based on clinical trial data, the most effective weight-loss injection available in the UK in 2026 is tirzepatide (Mounjaro), with an average weight loss of 22.5% of starting body weight after 72 weeks at the maximum 15 mg dose
Not too mushy, but definitely not raw
The medication may have an impact on embryo and fetal development (US FDA package insert)
Pulse rate: Elevated resting pulse above 100 bpm may indicate dehydration, electrolyte imbalance, or excessive stimulant intake (caffeine)