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Furthermore, Leu 5P forms an H-bond with Q302 7.32 via its main chain, while Ser 6P connects to ECL2 by forming an H-bond with E197 ECL2 , both residues contribute to ghrelin binding (Figs

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Experimental Neurology 322: 113064

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212,341 Consistent with this, transcriptomic analysis revealed that the Hedgehog signaling pathway is the most differentially activated pathway in young versus old hepatocytes after PHx, 342 which has also been verified in the context of diabetes-mediated liver disease