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2001 Mar;16(3):542-51

Based on the detection of the specific mutation, the BRAF/MEK inhibitors are used of in adjuvant targeted therapy

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In CD, the early and effective use of TNF- inhibitors has also been shown to prevent the development of disease complications, for example, strictures or penetrating ulcerations and disease progression, which led to a lower risk of surgery during disease progression and significantly reduced the risk of penetrating complications, but not stenosing complications [60]