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Excessive use of antisecretory medications like omeprazole, proton pump inhibitor, and antimicrobial agent

Other inflammatory mediators including tumour necrosis factor (TNF) and IL-13 also have a negative impact on gut barrier integrity by decreasing the expression of claudin proteins (Prasad et al

This limitation has been addressed by increasing serum UA in various ways, both pharmacological and genetic, including knockout of the uricase gene

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This status underscores the importance of sourcing from reputable, high-quality compounding pharmacies that adhere to stringent quality and purity standards