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Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, et al

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The natural levels of glutathione decline with age, stress, a poor diet, and exposure to environmental toxins

Our data suggest that, in addition to binding RUNX1 to regulate gene expression, enhancing RUNX1 binding affinity to its target DNA is an important mechanism by which CBF-SMMHC contributes to leukemogenesis, highlighting RUNX1-DNA interaction as a potential therapeutic target in inv(16) acute myeloid leukemia

An increased GSH content and activities of antioxidant enzymes such as SOD, CAT, GST, MDHAR, DHAR and GR which reduced oxidative stress and enhanced cadmium tolerance of exogenous spermine treated mung bean plant (Nahar et al