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Zhang et al., 2018), mutations in -Syn proteins undergo misfolding in transcription-translation to produce toxicity, and defective mitophagy further exacerbates neurotoxicity, leading to neuronal loss or damage (Ciron et al., 2015)

At the heart of FOXO4-DRI's mechanism of action is its ability to disrupt the interaction between the FOXO4 protein and p53, a key player in cell cycle regulation and apoptosis

Example weekly schedule (30mg vial) Week 1: 2.5mg dose Reconstitute 30mg vial with 3ml water Monday: Inject 0.25ml (25 units) Vial contains 29 doses of 2.5mg remaining Refrigerate, use over next 11 weeks Week 2-4 : Continue 0.25ml weekly Week 5 : Increase to 0.5ml (50 units) for 5mg dose Week 9 : New vial or continue (depending on dose progression) Dosing 40mg vials 40mg vials are bulk option