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Policies may vary by state due to tobacco regulations, including age restrictions and display rules

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Explore This Issue ACEP Now: Vol 43 No 10 October 2024 Toxins The plants major toxic alkaloid is nicotine, which binds to nicotinic acetylcholine receptors (nAChRs), is considered a psychostimulant, can produce analgesia and anxiolytic effects, and stimulates specific reward pathways in the brain at low doses

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