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(COPD) COPD COPD Original study:

Owing to the design limitations of the included studies, it is not possible to determine with certainty the clinical significance of changes in height on treatment, and how the observed changes in height and height velocity would differ from untreated patients

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demonstrate that hydrogen-rich saline inhibits lung injury by activating endogenous antioxidant systems through the NF-B/NLRP3 signaling pathway, reducing oxidative stress and mitigating local Fenton reaction(s) responsible for OH production [10, 30]

When all 30 of the CHF patients in that study subsequently received six weeks of oral thiamin therapy (200 mg/day), the average LVEF improved by 22%