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We did subsequent experiments showing that when we knock out key elements of the glutamate system, and glutamate is very important to plasticity, when we knocked out some of its receptors, the beneficial effects of liraglutide were substantially reduced
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10.1371/journal.pone.0080507 PLoS One 126 van Ettinger-VeenstraH.LundbergP.AlfldiP.SdermarkM.Graven-NielsenT.SjrsA.et al (2019)
Interest in triple receptor agonists is climbing fast
Additionally, they are all broken down similarly by dipeptidyl peptidase-4 (DPP-4) though GIP breakdown occurs at a slower rate than GLP-1 breakdown [16]
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