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Potential indirect causes include hypoglycemia or blood sugar fluctuations, gastrointestinal distress (nausea, vomiting), significant caloric restriction, sleep disruption, or pre-existing mood conditions

The announcement comes as Pfizer conducts dose optimization studies for ganuglipron, an oral GLP-1 drug also designed specifically for weight loss

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Help control appetite and cravings positioned as making it easier to eat less without feeling deprived, similar to the appetite-suppressing language used to market GLP-1 medications

Targets the inner membrane of mitochondria