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GP100130: Biotin-PDPN(74-85-Gly-Lys)-Tn(77) Mouse Pack Size:0.5 mg C92H146N22O34S / 2136

SKU: 75593725133

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Description

C92H146N22O34S / 2136

R) / α-Tocopherol-d3 Acetate

22 / A β-D-galactose ligand equipped with an azide-functionalized linker through a short ethyl spacer

producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics

/ Fmoc-Thr(Galβ(1-3)GalNAc)-OH (Peracetate) / TF Epitope (Threonine)

GP100130: Biotin-PDPN(74-85-Gly-Lys)-Tn(77) Mouse Pack Size:0.5 mg C92H146N22O34S / 2136C84H141N23O29S 1969. 2 PDPN (UniProt ID Q62011) synthetic Glyco dodecapeptide epitope (Glu74 Ser85 Gly Lys) that is present within the extracellular domain of the glycoprotein podoplanin. The glycopeptide fragment has tumor associated cancer antigen Tn at Thr77. Biotin was appended on the amine of the C terminal lysine. The posttranslational GalNAc modification is expressed by an aggressive fibrosarcoma, Ag104A, and is bound by Anti Tn Antigen

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