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M.KushnerR

In addition to these major depots, smaller amounts of WAT are present in other regions, including the bone marrow, subdermal areas, around blood vessels (perivascular), around the heart (epicardial), and in peri- and intermuscular spaces [19]

12 Of particular interest, a 20-week research trial involving nondiabetic patients with a mean body mass index of 30 to 40 kg/m 2 at baseline compared the weight loss effects of liraglutide versus orlistat 120 mg three times daily or placebo

Cardiovasc Res 53:304312 Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, Lan F, Diecke S, Huber B, Mordwinkin NM, Plews JR, Abilez OJ, Cui B, Gold JD, Wu JC (2014) Chemically defined generation of human cardiomyocytes

It is associated with a significant increase in serum inflammatory biomarkers such as C-reactive protein (CRP) and cytokines such as interleukin 1 (IL-1), IL-6, and tumor necrosis factor (TNF)