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Tirzepatide has a five-day half-life, and consistent weekly dosing produces the most stable blood levels

These medications work through distinct mechanisms to increase intestinal fluid secretion and accelerate transit

If this describes your experience, your dose may be too high

Different medications, even those in the same class, may have different side effects. Your healthcare provider can help determine whether adjusting your dose, slowing titration, or trying a different medication makes sense based on your symptoms and weight loss goals

During the initial weeks of semaglutide therapy and during dose escalations, when gastrointestinal side effects are most pronounced, abstaining from alcohol is advisable