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Phloretin suppresses carbohydrate-induced GLP-1 secretion via inhibiting short chain fatty acid release from gut microbiome

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These dosing conditions have been used in the oral semaglutide phase 3 trials and are part of the approved label

These drugs mimic the action of the natural GLP-1 hormone, which stimulates insulin secretion, inhibits glucagon release, slows gastric emptying, and reduces appetite

Before tossing out L-carnitine, consider whether the studies have looked at conditions that might be relevant to athletes or specific diets