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Since obesity, insulin resistance, liver fat, and metabolic dysfunction are closely linked, GLP-1 and glucagon-based combinations are being studied for their potential to reduce liver fat, improve metabolic markers, and slow disease progression

Searching for insulin-releasing peptides in the gut In the course of their research, Marks and Samols began to wonder whether the ingestion of glucose was due to an incretin-like substance originating from the gut which echoed with the incretin concept

These conditions warrant clinical assessment and management alongside Saxenda treatment

In the matched expanded populations, the mean age ranged from 59.2 to 69.2 years, 50.455.8% were female and the mean body mass index (BMI) ranged from 34.5 to 38.7 kg m 2