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While some studies confirm the expression of GLP-1R in the thyroid and suggest diversified effects across species, the currently available evidence does not allow for definitive conclusions regarding a significant risk of thyroid tumors associated with the use of GLP1 RAs (Table 1)

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Beyond minoxidil, other topical actives have shown promise in combination: copper peptides (Kuceki 2025) demonstrated significant results in resistant cases, platelet-rich plasma (PRP) has been studied in network meta-analyses, and GHK-Cu serums work through complementary mechanisms