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383,384 Dotinurad, a selective urate reabsorption inhibitor available in Japan, inhibits URAT1 with high selectivity, demonstrating non-inferiority to febuxostat in lowering serum UA levels with no significant safety concerns 385 (Table 4)

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Citizens have questioned enforcement of the new law, citing corruption and noting that many will continue smoking in their private residences

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The royal familys relationship with the press was also addressed in series one, and viewers witness two moments in which great respect is shown for the monarchys privacy